Treatment option · Testosterone Therapy

Testosterone pellets with Pellecome

Short answer

Testosterone pellets are small implants placed under the skin of the hip or lower abdomen through a tiny numbed incision in a short office visit. They release testosterone steadily for months; FDA-labeled pellets are dosed every 3 to 6 months. Bruising is common and a pellet occasionally works its way out. Once placed, the dose cannot be turned down until the next insertion.

By the Ultimate Male team · Updated October 8, 2026

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What pellet therapy is

Testosterone pellets are compressed testosterone about the size of a grain of rice. They are placed in the fat layer under the skin, where they dissolve slowly and release testosterone for months. MedlinePlus notes that pellets are implanted by a doctor or nurse rather than taken at home.

Ultimate Male uses pellets from Pellecome, a partner supplier of compounded hormone pellets. Compounded pellets are made to order and are not themselves FDA-approved products; the FDA-approved pellet, Testopel, is the reference point for most published dosing and safety data. Your provider explains which product you receive and why.

Who pellets suit, and who should choose something else

Pellets tend to suit men who:

  • Have stable, confirmed low testosterone and already know they respond well to treatment
  • Want to stop thinking about weekly shots or daily capsules
  • Travel often or have schedules that make regular dosing hard

They are a weaker fit if you are new to testosterone and your dose has not been established, because there is no quick way to lower a pellet dose. Like all testosterone, they are not for men with breast or prostate cancer, and not for men trying to conceive. Men who bleed easily, take blood thinners or have skin problems at the usual sites need individual review. Our comparison of testosterone injections versus pellets sets out the trade-offs.

The in-office insertion, step by step

The procedure takes place in a regular treatment room and is usually short.

  1. Positioning. The site is usually the upper buttock, hip or lower abdomen, in an area that will not take direct pressure.
  2. Cleaning and numbing. The skin is cleaned and a local anesthetic is injected, so you feel pressure rather than pain.
  3. Small incision. A tiny cut, a few millimeters long, opens the skin.
  4. Placement. A narrow insertion tool guides the pellets into the fat layer, often spreading them in more than one track.
  5. Closure. The incision is closed with adhesive strips and covered with a pressure dressing.

You drive yourself home. Your provider explains limits on strenuous activity and on soaking the site, since early heavy exercise is a known trigger for a pellet working its way out. Our guide to pellet insertion and what to expect walks through recovery day by day.

How long one insertion lasts

The Testopel label gives a replacement dose of 150 to 450 mg under the skin every 3 to 6 months, with the number of pellets based on your testosterone needs. That range shows how much the timing varies. Your number of pellets, your activity level and how quickly your body clears testosterone all shift when a set wears off.

How long a Pellecome insertion lasts for you is estimated at the consultation and then confirmed with labs, rather than assumed from a calendar. The AUA guideline recommends a first testosterone check two to four weeks after the initial implant and a second one at about 10 to 12 weeks. Those results, with your symptoms, decide how many pellets go in next time and when. Our page on when testosterone pellets wear off covers the signs.

Why the dose cannot be adjusted until next time

With injections or capsules, a high result can be fixed at the next dose. With pellets, the testosterone is already in place and releasing. If your level runs high, or hematocrit or estradiol climbs, the options are limited to waiting, managing the side effect and lowering the count at the next insertion. Surgical removal is possible but is not routine; our page on whether pellets can be removed explains why.

For that reason, your provider may suggest settling your dose with injections or capsules before a first pellet visit, and the first insertion is usually dosed on the cautious side.

Bruising, extrusion and other risks

Risk What it looks like How common
Bruising and soreness Tenderness and discoloration around the site Common in the first days
Extrusion A pellet works back out through the incision 5% to 12% of procedures in one randomized study
Infection Redness, warmth, drainage, fever Less common; needs prompt review
Fibrosis A firm area under the skin Reported after insertion

In a randomized study of 246 implant procedures, extrusion occurred after 12% of hip insertions and 5% of abdominal ones, and one operator had markedly fewer complications than others, a reminder that technique matters. The Testopel label lists infection, bleeding, bruising, fibrosis, drainage, itching and pellet extrusion among reported site reactions. If a pellet comes out, keep it and call the clinic; our page on what to do if a pellet came out has the details.

Testosterone’s whole-body effects still apply: rising hematocrit, higher blood pressure, acne and breast tenderness are monitored as with any form. Chest pain, sudden breathlessness or a hot, swollen calf are emergencies; call 911.

Paying for pellets and booking

Ultimate Male is direct-pay and does not bill insurance or publish prices. You pay per visit with no membership, and plans covering several insertions can be bundled. Our page on testosterone pellet cost explains what drives the total. Itemized receipts support FSA, HSA and out-of-network claims, and CareCredit, Prosper Healthcare Lending and Afterpay offer financing. Arcadia Police Officers Association members receive 13% off TRT.

If you like the idea of a few visits a year instead of weekly dosing, start by confirming your dose. Call 626-319-5261 or book a pellet consultation at San Gabriel or Downey, and your provider will tell you whether pellets make sense now or after a period on another form of testosterone therapy.

questions

Common questions.

Testosterone pellets with Pellecome

Still unsure? Take the free assessment

Can pellets be removed if my levels run too high?
Removal is possible but not simple, because pellets soften and break down in the tissue. That is why the first insertion is usually dosed conservatively and checked with labs.
Will I see the pellets under my skin?
Usually not. They sit in the fat layer, and the small incision typically heals to a faint mark. Some men can feel a slight firmness at the site for a while.
Do pellets affect fertility like other testosterone?
Yes. Any testosterone from outside the body suppresses sperm production, so pellets are not a choice for men trying to conceive.

This page is general education, not medical advice. A licensed clinician must review your symptoms, history and labs before any treatment decision. For chest pain, trouble breathing, signs of stroke or an erection lasting over four hours, call 911.

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