Answer · Testosterone Therapy

Do I have to give myself testosterone injections?

Short answer

No. At Ultimate Male, injectable testosterone can be given in clinic as well as at home, and two routes avoid regular needles altogether. Kyzatrex is a testosterone capsule taken by mouth with food, and Pellecome pellets are placed under the skin to release testosterone over several months. Which route fits depends on your labs, schedule and health history, decided at your consultation.

By the Ultimate Male team · Updated October 8, 2026

Man doing a heavy dumbbell row in the gym

What are your options if you dislike needles?

You have four, and only one asks you to inject yourself. The testosterone therapy program at Ultimate Male uses injections, the oral capsule Kyzatrex and Pellecome pellets, and injections can be done at the clinic or at home.

Route Needles involved How often Who does it
Injections in clinic A shot at each visit On the schedule your provider sets Clinic staff
Injections at home A shot on each dose day On the schedule your provider sets You, once you have been shown how
Kyzatrex capsules None Taken by mouth with food, usually twice a day You
Pellecome pellets A numbing shot and a small insertion Every few months A clinician, in the office

If self-injection is the only thing holding you back from treatment, you do not have to choose it. Our page for men who dislike needles covers the practical side in more detail.

What do in-clinic injection visits involve?

You come in, a member of the clinical team gives the injection, and you go back to your day. Nothing is handed to you to manage at home. The trade-off is the schedule: you need to get to the San Gabriel clinic during its hours (Tuesday, Thursday and Friday, 10 AM to 6 PM) or arrange a Downey appointment.

How often you would come in depends on the dose schedule your provider sets, which is decided after your labs and consultation. Ask about this on the free call so you can judge whether in-clinic visits fit your week. Our comparison of injections at home vs in clinic lays out the pros and cons.

How do Kyzatrex and pellets compare?

They solve the needle problem in different ways. Kyzatrex puts the routine in your hands every day, while pellets take it out of your hands for months.

Kyzatrex. The Kyzatrex label gives a usual starting schedule of one dose in the morning and one in the evening, taken with food; your provider sets the dose. Testosterone is checked 7 days after starting or after a dose change, with blood drawn 3 to 5 hours after the morning dose, and blood pressure is monitored periodically. The label lists its boxed warning on blood pressure increases as removed in July 2025, but blood pressure checks remain part of care. See our Kyzatrex page for more.

Pellets. Pellets are placed under the skin during a short in-office procedure. For the FDA-approved pellet product, the Testopel label says the effect usually lasts three to four months and sometimes up to six. It also reports infection and pellets working their way out, mostly in the first month. Ultimate Male uses Pellecome pellets; our testosterone pellets page and our guide to what pellet insertion is like cover the visit.

What if you want to learn to self-inject later?

That door stays open. If you start with in-clinic injections, capsules or pellets, you can still learn to inject yourself later if it would suit your schedule better. The under-the-skin method uses a shorter, thinner needle than a shot into muscle; our page on whether subcutaneous testosterone is effective explains the under-the-skin option.

Each has its own set of things to watch, which is why labs follow every route. All of them need follow-up checks of testosterone levels and blood counts, and the FDA’s 2025 class-wide labeling changes confirmed that blood pressure rises with all testosterone products, so blood pressure is checked whatever the route. Your provider explains the monitoring for the one you choose.

Choosing your route at Ultimate Male

Start with the free 10-minute phone call and mention that you would rather not inject yourself. After same-day labs and your one-on-one consultation, the provider lays out which routes suit your numbers and health history, how often you would need to come in, and what monitoring looks like.

Ultimate Male is a direct-pay clinic with itemized receipts for FSA and HSA accounts and financing through CareCredit, Prosper Healthcare Lending and Afterpay. Ask for a quote for the route you choose before you book.

questions

Related questions.

Do I have to give myself testosterone injections?

Still unsure? Take the free assessment

Does pellet insertion involve a needle?
Yes, briefly. The skin is numbed before the pellets are placed, so there is a numbing injection and a small insertion, but then nothing more until the next round months later.
Is HCG an option if I want to avoid needles?
Not really. HCG (Pregnyl) is also given by injection, so it does not solve a needle problem, though some men use it alongside other routes for fertility reasons.
Can I switch routes later?
You can. Changing routes is a conversation with your provider, followed by labs to check how the new route is working.

Sources

  1. KYZATREX (testosterone undecanoate) capsules label · DailyMed, National Library of Medicine
  2. TESTOPEL (testosterone) pellet label · DailyMed, National Library of Medicine
  3. FDA issues class-wide labeling changes for testosterone products · U.S. Food and Drug Administration

This page is general education, not medical advice. A licensed clinician must review your symptoms, history and labs before any treatment decision. For chest pain, trouble breathing, signs of stroke or an erection lasting over four hours, call 911.

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