Lab test · Blood Testing

Comprehensive metabolic panel (CMP)

Short answer

A comprehensive metabolic panel is a routine blood test that reports 14 values. They fall into four groups: kidney markers (creatinine and BUN), liver markers (ALT, AST, alkaline phosphatase, bilirubin, albumin and total protein), electrolytes with calcium, and glucose. In men, a single mild abnormality after hard training, dehydration or a non-fasting draw often just needs a recheck, while larger or clustered changes need a visit.

By the Ultimate Male team · Updated October 8, 2026

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What does a CMP measure?

A CMP is a single blood draw that reports 14 values about how your body handles fuel, fluid and waste. MedlinePlus describes it as a routine test that checks liver and kidney health, blood glucose, protein levels and electrolyte balance.

It is easiest to read in four sets. The typical adult ranges below come from the MedlinePlus encyclopedia, which notes that ranges vary slightly among labs, so use the range on your own report.

Set Value Typical adult range
Kidney Creatinine 0.6 to 1.3 mg/dL
Kidney BUN (blood urea nitrogen) 6 to 20 mg/dL
Liver ALT 4 to 36 U/L
Liver AST 8 to 33 U/L
Liver Alkaline phosphatase (ALP) 20 to 130 U/L
Liver Total bilirubin 0.1 to 1.2 mg/dL
Liver Albumin 3.4 to 5.4 g/dL
Liver Total protein 6.0 to 8.3 g/dL
Electrolytes Sodium 135 to 145 mEq/L
Electrolytes Potassium 3.7 to 5.2 mEq/L
Electrolytes Chloride 96 to 106 mEq/L
Electrolytes CO2 (bicarbonate) 23 to 29 mEq/L
Electrolytes Calcium 8.5 to 10.2 mg/dL
Glucose Glucose 70 to 100 mg/dL

What do the kidney values tell you?

Creatinine and BUN are waste products your kidneys clear, so they rise when filtering slows. Creatinine is also the starting point for your eGFR, the number most often used to stage kidney function.

Creatinine has a known blind spot in active men. MedlinePlus notes that a high creatinine does not always mean a kidney problem, and that dehydration, intense exercise and a diet high in meat can raise it. The National Kidney Foundation adds creatine supplements and high muscle mass to the list. Our pages on eGFR and creatinine and the cystatin C test explain how to get a cleaner kidney reading.

What do the liver values tell you?

ALT and AST are enzymes that leak from damaged liver cells, ALP rises with bile flow problems and with bone growth or repair, and bilirubin reflects how well the liver clears old red-cell waste. Albumin and total protein reflect what the liver makes.

Two patterns are common and usually benign in men. ALT and AST can rise after heavy lifting because muscle contains them too, which our page on high liver enzymes after lifting covers. A mildly high bilirubin with normal enzymes is often Gilbert’s syndrome. When ALP is high and the source is unclear, a GGT test helps separate liver from bone.

What about electrolytes and glucose?

Sodium, potassium, chloride and CO2 track your fluid and acid-base balance, and calcium reflects bone, parathyroid and kidney function. Large shifts in these values can affect the heart and nerves, so they get attention quickly.

Potassium has a well-known false alarm. The MedlinePlus potassium page notes that repeatedly clenching and relaxing your fist during a draw can temporarily raise the level. Glucose is only interpretable when you know whether you fasted, and a fasting result above the range is a reason to check HbA1c rather than to diagnose from one value.

Recheck or visit: how to triage an out-of-range result

Context decides most of this. One value slightly outside the range, with a plausible reason, usually earns a repeat test. Several abnormal values together, a large deviation or new symptoms call for a provider visit.

Finding Usually means Common reason in men
Creatinine slightly high, everything else normal Recheck, often with cystatin C Muscle mass, creatine, hard training, dehydration
ALT and AST mildly high after a heavy week in the gym Recheck after a few easy days Muscle breakdown from training
Bilirubin mildly high, enzymes normal Recheck, usually benign Gilbert’s syndrome, fasting
Potassium high with a difficult draw Recheck Fist clenching during the draw
Fasting glucose above range Visit and HbA1c Insulin resistance or prediabetes
ALT or AST well above range without a training explanation Visit Fatty liver, alcohol, medicines, supplements
Several kidney or liver values abnormal at once Visit Needs a broader workup

Severe symptoms such as chest pain, confusion, fainting or yellowing of the skin and eyes are not a recheck situation. Call 911 or get to the nearest emergency department. Our page on next steps after abnormal blood work covers the in-between cases.

How Ultimate Male uses the CMP values

Liver and kidney function are part of the Targeted Preventative Health Panel and the 40+ biomarker Comprehensive Health Optimization Panel, both drawn on site at our San Gabriel and Downey clinics. Ask on the free call which of the 14 CMP values your chosen panel reports, and mention your training, supplements and fasting plans so the results can be read correctly.

Your PA-C or MD goes through each set at the consultation and separates the numbers that need a simple repeat from the ones that change your plan. Our liver and kidney function panel page describes that panel, and the full menu is on our preventative blood testing page.

questions

Common questions.

Comprehensive metabolic panel (CMP)

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What is the difference between a CMP and a BMP?
A basic metabolic panel covers 8 of the 14 CMP values. MedlinePlus notes that it leaves out total protein, albumin, bilirubin and the three liver enzymes, so it says much less about the liver.
Does a normal CMP mean my kidneys and liver are fine?
It is reassuring but not complete. MedlinePlus notes that creatinine can stay in range during early kidney disease, so your provider may add eGFR, a urine albumin test or other markers based on your risk.
Do I need to fast for a CMP?
Often, yes. MedlinePlus says you may need to fast for several hours, mainly so the glucose value is interpretable. Water is usually fine, but follow the instructions you are given.

Sources

  1. Comprehensive Metabolic Panel (CMP) · MedlinePlus, National Library of Medicine
  2. Comprehensive metabolic panel · MedlinePlus Medical Encyclopedia
  3. Creatinine Test · MedlinePlus, National Library of Medicine
  4. Potassium Blood Test · MedlinePlus, National Library of Medicine
  5. Creatinine · National Kidney Foundation

This page is general education, not medical advice. A licensed clinician must review your symptoms, history and labs before any treatment decision. For chest pain, trouble breathing, signs of stroke or an erection lasting over four hours, call 911.

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