What series did the studies use?
The two double-blind, placebo-controlled trials that most people cite used the same basic schedule: two sessions, one month apart. Neither tested three, four or more sessions against two, so the research cannot tell you whether more is better.
| Study | Men | Sessions | Spacing | When results were judged |
|---|---|---|---|---|
| 2021 trial, mild to moderate ED | 60 | 2 (10 mL each) | 1 month | 1, 3 and 6 months after the series |
| 2023 trial, mild to moderate ED | 61 | 2 | 1 month | Main result at 1 month after the second injection; also 3 and 6 months |
The 2021 study reported a meaningful improvement in 69% of men on PRP against 27% on placebo at six months. The 2023 study found no difference from placebo. So the same two-session schedule produced a positive result in one trial and a negative one in the other.
Why is there no standard number?
PRP for ED has no approved protocol to follow. The AUA erectile dysfunction guideline classifies it as experimental, and it is not FDA-approved for this use. Without an approved label or guideline, there is no official dose, volume or session count.
PRP is also not a standardized drug with a fixed strength. It is made from your own blood at each visit, and what ends up in the syringe depends on the system used to prepare it. The International Society for Sexual Medicine describes the evidence as mixed and calls for more research. A series length quoted with great confidence is a choice, not a proven standard.
When should you judge whether it worked?
Give it time after the last session, not after the first. Both trials took their first measurement about a month after the series, and the 2021 study followed men to six months. A sensible plan does the same: an early check around a month after your final session, and a second look a few months later.
It helps to track your symptoms before you start, so the comparison is honest. Our guide to tracking symptoms before a men’s health visit shows a simple way to do it. Keep in mind that men in the 2021 trial stopped other ED treatment during the study; outside a trial, your provider decides whether your current treatment continues.
What decides your number at Ultimate Male?
Your series is set at the consultation, not from a fixed package. The factors that shape it include:
- Severity. The trials only studied mild to moderate ED.
- Cause. ED from reduced blood flow is a different problem from ED after nerve damage or from medication side effects.
- What else is in the plan. PRP may stand alone or sit alongside pills, shockwave or testosterone therapy. Our page on combining shockwave and PRP explains how that changes the schedule.
- Your response. How you are doing after the first sessions guides whether more makes sense.
Every session repeats the same routine: a small blood draw, a spin in the centrifuge to concentrate the platelets, numbing, then the injection. Mild soreness for a day or two is normal, and most men go back to their usual day afterward. That makes each visit easy to fit in, but it also means each extra session is a real visit, not a quick add-on.
Because the number of sessions drives the total, ask for a quote once the plan is set. Our page on the cost of PRP for ED explains what goes into it.
Next step
Start with the free 10-minute phone call, then labs at our San Gabriel or Downey clinic and a one-on-one consultation with a PA-C or MD. If PRP fits, you will know the planned number of sessions, the spacing and when results will be reviewed before you commit.
If you want the evidence first, read whether PRP for ED actually works and how PRP is prepared. When you are ready, the PRP injections page has booking details.
